Walt I've thought about this a lot. Basically a strategy layer where you build up a galactic empire, fighting individual battles with the fleets you design. Controlling sectors would earn you money, crew, resources, and supplies (food) over time that you would use to maintain and expand your fleet. Ideally you would be able to construct your own mining, farming, and construction ships/stations, but the problem then becomes how to integrate the ship simulation mechanics with the strategy layer mechanics in a way that makes station design important (like for determine farming speed, mining speed, and construction speed), and I'm not sure how to do that.
you could run mining simulations like you would run a battle, in real time.
so when it is your turn you can design your mining ship and then run a real time battle against time where you need to mine the maximum ore you can mine with your miner ship design and come back as fast as possible to the station.
the quantity of ore you mine and the time it takes to come back and deliver the ore will be the amount you get per X turn. X depending on the time it took to mine all of this.
then you can proceed to build your mining ships for future mining.
with this system you could mine with precision the right amount you want in a particular given time.
with this system you could also make some special mining battle event where some region would have rare environmental hazard like asteroid everywhere or slowing effect nebula with which you would also need to do a Ore gathering time battle to set what you will get mining there with your current design.
as for the AI they can either have some generic ressource collecting depending on stats and numbers or a pre calculated simulation depeinding on their design using the same factor as the player. (+ a little bonus because its the AI :p)
aside for some few particular mining site all of them should be the same to avoid having tu run a mining battle for each mining zone.
this system would automaticaly calculate what you get from several mining ships without looking at them buming into each other in real time.
but all this may work only if your station (which would also be totally handcrafted by the player unless he use the generic base station provided by the game?) is always set at the same distance from the Ore to mine.
with this minigame style gameplay you could even add social events like a racing event where you compete with your racing ship against some AI to win some prize cash! (unless you are at war with that empire, etc.. )