I was able to click buttons in the game without seeing what i'm doing, alt-tab to view the changes, and repeat, in order to play around with the graphics settings and the only thing that lets me play is "Resizable window", the fullscreen options don't work.
I also tried toggling these but they didn't seem to do anything: Pause when window loses focus, Trap mouse cursor
I'm on 0.15.1a_standalone